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no human validation Approach Published mouse regimen Pattern 5 mg/kg IP, ~3x/week Duration Several weeks Notes Animal only

Methylfolate (also called L-Methylfolate, 5-MTHF, or (6S)-5-MTHF) is the only type of folate that can cross the blood-brain barrier, which makes it particularly effective in regulating dopamine and serotonin levels (2)

In addition, iron and other metal ions are cofactors of many proteins

Its well-documented interaction with multiple cellular pathways makes it one of the more versatile peptides available for investigative use

When do you take your peptides

Although these studies proposed different sources for lactylation substrates, the regulatory impact of protein lactylation on gene expression has since been widely confirmed