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L-Carnosine is best known for its anti-aging effects, skin health benefits, and cellular protection

The mitochondrial origin connects MOTS-c directly to cellular energy metabolism and positions it as an endogenous regulator of metabolic function

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We then evaluated the induction of lipid ROS in the cells to verify the activation of ferroptosis

Up to 80% of cancer patients have cachexia, and it has been estimated that more than 30% of cancer patients die due to cachexia [5, 6]