Relative contraindications requiring careful consideration and enhanced medical supervision include history of pancreatitis, severe gastrointestinal disease including gastroparesis, diabetic retinopathy (requires ophthalmologic monitoring during therapy), severe kidney disease, history of suicidal ideation or severe depression, gallbladder disease or history of cholecystitis, and age under 18 years
Internal hemorrhoids may cause bleeding during bowel movements, often appearing as bright red blood on toilet paper or in the toilet bowl
Mediterranean diet
It enhances insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways
The study identified a higher number of patients with retained gastric contents in those undergoing EGD alone compared to no gastric contents in those undergoing combined EGD-colonoscopy ( It is unclear if the risks are lower with the combination of holding the medication and also having a bowel prep, if one of these approaches may be sufficient to reduce risks, or if even a clear liquid diet without a bowel prep could also be just as effective
Because both constipation and diarrhea are risk factors for hemorrhoids , people taking semaglutide should be aware of their bowel habits and take steps to prevent problems
