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Notably, this study was conducted in different regions of Europe with different Se levels, so it is unclear whether the effectiveness of Se and the generalizability of the result were confounded by other confounding factors such as the effect of baseline Se levels

It has also been shown to decrease oxidative stress in the eye and delay age-related changes, including loss of visual acuity and the incidence of cataracts [12]

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Another important consideration is that high-dose folic acid can mask the haematological signs of B12 deficiency while allowing neurological damage to progress

Edwards, CPC, CEDC , is a member of the 2013-2015 AAPC National Advisory Board, representing the Northeast Region