General refrigeration principles for peptide injectables: Store in the main body of the refrigerator , not in the door compartment, where temperatures can fluctuate more significantly Do not place directly against the back wall of the refrigerator, as this area may be prone to freezing Keep in its original packaging to protect from light Do not freeze freezing can cause irreversible structural damage to the peptide molecule Do not shake or agitate the product before or after refrigeration Some approved peptide injectables permit short-term storage at room temperature once in use (for example, below 25C or 30C for a defined number of days), as stated in their SmPCs
In other news today, Novo Nordisks legal battle with KBP Bio is heading to arbitration after Singapores Court of Appeal upheld an injunction against the biotech and its founder, Dr Huang Zhenhua
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However, continued shortages of these drugs have raised concerns among patients and healthcare providers alike
A gradual reduction approach might involve stepping down through lower doses over several months
Dosage Considerations and Administration Routes In clinical trials of GLP-1 peptide Cagrilintide, it is injected under the skin, and the doses are usually started low and gradually increased until they reach effective levels over a number of weeks
