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Thirty healthy men fasted on the same day of each week for 3 weeks straight, during which time they were given either a high (250 mg) or low (100 mg) dose of Amarasate twice daily, with both groups showing a significant decrease in self-reported measures of hunger by at least 10%

There have been rare postmarketing reports of pulmonary aspiration in patients receiving GLP-1 receptor agonists undergoing elective surgeries or procedures requiring general anesthesia or deep sedation who had residual gastric contents despite reported adherence to preoperative fasting recommendations, the new labels will indicate