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3.6.3 Mechanisms linking gut dysbiosis to PSCI 3.6.3.1 Neuroinflammation Gut dysbiosis and increased intestinal permeability following ischemic stroke (IS) have been linked to systemic endotoxemia and altered microbial metabolite signaling, potentially exacerbating neuroinflammation and injury (Zhang W

Modulation of autophagy Autophagy is engaged in intracellular material recycling to sustain cell bioenergetics 58

The study then investigated DSIPs ability to protect against hypoxia-induced mitochondrial dysfunction

Higher doses may necessitate divided dose (twice/day) administration

Protects cells from oxidative stress and environmental damage

L-Glutathione Reduces melanin and detoxifies skin