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The trial tested oral administration primarily, and no controlled study has tested subcutaneous injection in humans

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Physiologically, GLP-1 plays a central role in glucose homeostasis by stimulating insulin secretion, suppressing glucagon release, slowing gastric emptying, and promoting satiety

Research demonstrated elevated TRPM4 expression in ox-LDL-treated HCAECs, while TRPM4 knockdown reduced intracellular iron levels and ferroptosis-related protein expression (33)