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Publisher American Journal of Sports Medicine Accessed Jun 27, 2026 Study type Systematic Review Limitations: A clinician primer is contextual

M., Wang, C

The B12 vitamin is important for healthy normal blood, cells and nerves

Modulation of cellular signaling pathways involved in intracellular communication Influence on growth factor sensitivity and signal amplification Regulation of gene expression patterns in controlled cellular models Interaction with mitochondrial processes related to ATP production Support of enzymatic activation and substrate sensitivity Primary Research Applications Regenerative Cell Biology: Used in controlled in-vitro environments to study cellular repair pathways, matrix interactions, and signaling responses associated with cellular regeneration models

The mechanism appears to involve the nitric oxide (NO) system

Vitamin B12 helps the body utilize fats and carbohydrates while supporting protein production, making it an important component for overall metabolic health