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Why pulsatile and endogenous matters Because these analogs stimulate the pituitary rather than replacing GH, the resulting secretion tends to preserve the bodys natural pulsatile rhythm and remains subject to normal feedback control somatostatin, IGF-1 negative feedback, and the finite secretory capacity of the gland

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In Mexico for example, 18 were identified, which are also of common appearance in other regions like the African continent, the south of Europe and the Southeast Asia 39