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Raza FA, Altaf R, Bashir T, et al

For T4 treatment, MMI mice received daily T4 injection at a dose of 0.6 g/g/day for 5 days and were then euthanized 24 h after last T4 injection

That means at least 12-16 weeks at or near the maximum tolerated dose

Conversely, at current prices, GLP-1 RAs are unlikely to meet the arbitrary AU$28,000 per QALY willingness-to-pay threshold in either the total or secondary prevention population when considering only their benefits on CVD

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