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Published pharmaceutical literature describes the physiological response to injected endotoxins: fever (pyrogenic response), injection-site inflammation, and systemic inflammatory markers at higher exposure levels

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Interestingly, the interaction of Sec24C and SLC7A11 is enhanced by VRK2-mediated phosphorylation, which is consistent with previous studies showing that the phosphorylation of Sec24C determines its affinity to cargo proteins and intracellular transport of cargoes [25]

The modified protocol demonstrates superior performance characteristics compared to conventional GPx assays, including elimination of interference effects, enhanced accuracy and precision, and improved reproducibility across diverse sample matrices

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[DOI] [PMC free article] [PubMed] [Google Scholar] 170.Checconi P., De Angelis M., Marcocci M.E., Fraternale A., Magnani M., Palamara A.T., Nencioni L