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Deodhar A, Sliwinska-Stanczyk P, Xu H, et al

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This could indicate a more serious reaction that requires medical attention

PCD represents a special category of regulated cell death (RCD), which is a more broadly defined category as a cell demise occurring in an orderly fashion through a well-coordinated genetically encoded machinery in response to a wide spectrum of internal and external perturbations [2]

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For plan sponsors, these differences highlight the importance of balancing efficacy with tolerability, as side-effects can directly influence adherence and total cost of therapy