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The diet and medication may need to be adjusted based on blood test levels

Whereas fMRI does not allow inferences on neurotransmission, these results are well in line with work in animals (Decarie-Spain & Kanoski, 2021

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Metformin) with diagnosis of type 2 diabetes Documented history of lifestyle intervention Quarterly clinical review to assess improvement (weight loss or A1C) Discontinuation if there is no measurable improvement after 6 months 3

Going over how to handle pain is a key part of learning about the medication, not an afterthought

I encourage clients to focus on a diet that is richer in vegetables over fruit, as well as a healthy intake of essential fatty acids, lean proteins and whole grains