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Moreover, due to their intrinsic affinity for bone tissue, calcium oxide nanoparticles (which transform into nano-sized hydrated calcium hydroxide upon contact with physiological solutions) 122,123 produce an immediate change in the acid-base balance of the local environment

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The 3-Month TB-500 Cycle: Loading, Maintenance, and Break The 3-month cycle structure used by clinical providers follows the biological requirement for sustained tissue signaling