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Although the term PEM allows one to deal with diagnostically challenging pigmented melanocytic tumors, for which a reliable distinction between melanoma and an unusual pigmented nevus is difficult or impossible by light microscopic examination alone, we caution against labeling lesions as PEM, which previously would have been diagnosed as benign EBN or pigmented dermal spindle and epithelioid cell nevus

Melatonin Melatonin is an endogenous hormone primarily synthesized in the pineal gland from tryptophan [62]

Arlington, VA, USA: 2013

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