The metabolic cost of neural information
4.1 Signals of adverse events We observed that metabolic and nutritional adverse reactions were more frequently reported by females (Table 1), which has previously been interpreted as a greater inclination for females to report AEs to FAERS ( Exenatide (n = 10,450), dulaglutide (n = 4,847), liraglutide (n = 2,860), semaglutide (n = 2,905), and tirzepatide (n = 1,089) had the greatest number of reported AEs, and the highest number of AEs reported on the effects of appetite, as reflected in our analyses of the HLT stratum (Supplementary Table S2)
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[] The neurobiological mechanisms associated with schizophrenia include abnormalities in glutamatergic neurotransmission, indicated by decreased concentrations of glutamate in the brain and receptor NMDA malfunction
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The detection of neuro filament light chains (NFL) in biological samples is emerging as good neuronal biomarkers, however, techniques and kits for reliable detection are still limited, and more research studies are needed to explore their ability to differentiate between different neurodegenerative diseases (Gaetani et al., 2019)