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This is structural evidence that movement of Y296 is associated with binding of NADPH and suggests that this residue may be acting to block the active site FAD from non-specific reduction and/or reoxidation and thus confines the redox activity of reduced SmTGR

Maybe a pound or two

Weeks 24 through 36 showed continued loss but at a decelerating rate

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The data is representative of three independent experiments and the standard deviation was calculated