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The deals with the drug makers are part of a wider initiative to bring drug prices paid by Americans closer to prices paid in other developed countries a concept sometimes called most favored nation pricing.

This proton transport results in the establishment of an energy gradient (proton motive force, PMF) which is used to power the synthesis of ATP from ADP and inorganic phosphate (P i ) as the protons flow down the gradient back into the matrix through the ATP synthase complex

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