[1] Peptides and Gut Microbiome The gut microbiome is a complex and dynamic ecosystem composed of bacteria, viruses, fungi, and other microorganisms that interact closely with host physiology
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Those most at risk include vegans and vegetarians, people with digestive conditions such as Crohn's disease, coeliac disease or IBS, those taking long-term metformin or proton pump inhibitors, older adults whose ability to absorb B12 through the gut declines naturally with age, those with pernicious anaemia, and anyone with a history of chronic alcohol use
Chromatin immunoprecipitation sequencing and RNA sequencing identified a variety of autophagy genes (Atgs), including Atg2, Atg4, Atg7, and Atg10, as direct p53 target genes