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Semaglutide For Weight Loss Semaglutide was first approved in 2021 by the United States Food and Drug Administration (FDA) to treat obesity.[2,5] Prior to this, semaglutide had been FDA-approved for treatment in type 2 diabetic patients in 2017 as an injection and as an oral formulation in 2019.[7,8] The brand name of semaglutide for use in patients who are obese or overweight with a comorbid condition is Wegovy.[2] Dosing And Administration Semaglutide is a subcutaneous injection that is given once weekly in the abdomen, thigh, or upper arm.[2] The starting dose is 0.25 mg once a week for 4 weeks

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