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If thigh injection reduces nausea enough to keep you compliant with your protocol, the slightly slower absorption becomes irrelevant compared to the benefit of actually staying on treatment

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For example, in the SELECT trial (17,600 patients with cardiovascular disease and obesity but without T2D), weekly subcutaneous Semaglutide (2.4 mg) reduced the risk of major adverse cardiovascular events (MACE heart attack, stroke, or cardiovascular death) by 20% compared to placebo (HR 0.80

MNT had the opportunity to speak with Babak Firoozi, MD, a board certified gastroenterologist at MemorialCare Orange Coast Medical Center in Fountain Valley, CA, about this study

The Weekend Strategy Some users plan their injection for Friday morning