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If no nausea occurs, the dose can be increased by 50-100mcg weekly until reaching 250-500mcg or until clinical endpoints are achieved

S2c, Table S1a)

This finding provides insight into how the ER sets redox balance and provides a framework to define how ER metabolism is controlled and coupled to ER function in physiology and disease

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Cancer cells, including PDAC cells, exhibit an increased demand for iron to support their accelerated proliferation

Differential expression analysis of snRNA-seq data was performed using DESeq2 (v1.30.1) 28 Wald tests with BH correction