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Spider veins, also called telangiectasias, are tiny visible vessels just underneath the skin

# Statistically significant difference from RG group

Merrill, L., Malley, S

1 If anti-intrinsic factor results are negative but suspicion for pernicious anemia remains, an elevated serum gastrin level is consistent with the diagnosis

Salmon JH, Rat AC, Sellam J, Michel M, Eschard JP, Guillemin F et al (2016) Economic impact of lower-limb osteoarthritis worldwide: a systematic review of cost-of-illness studies

Understanding these mechanisms helps patients recognize that cold sensitivity is often a normal physiological response to body composition changes rather than a concerning medical problem