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Tsuji-Naito et al 27 demonstrated that DHLHZn (sodium zinc dihydrolipoyl histidinate, compound of Zn2+/dyhydrolipoic acid derivative complex, which was developed for cosmetic/medical use) serves as a potentially effective skin-lightening agent, an effectiveness that is based on the compounds covalent scavenging of DOPAquinone, resulting in depigmentation

In the present study, we extend these findings by showing livers from GCLM KO mice exhibit a persistently greater level of oxidant stress as measured by protein carbonylation and expression of redox-sensitive genes

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