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Luo et al., Epigenetic suppression of PGC1 (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas

The distinct feature that sets these branded GLP-1s apart in the realm of weight management is their ability to influence satiety and reduce appetite

In a cohort study of 125,474 patients initiating GLP-1 RAs in the United States, 64.8% of patients without type 2 diabetes discontinued within one year (Goodwin Cartwright et al., 2025)

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Conclusions This review provides insights into the influence of DPP-4 on bone metabolism and delineates the potential mechanisms of the interaction between DPP-4 and bone (Fig