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This breakthrough has accelerated research into riboflavins role not only as a conventional dietary supplement to correct metabolic deficiencies, but also as a component of gene therapy approaches and enzyme-targeted precision medicine

"The 4 gram per day recommended dose is also the maximum safe dose, one that must not be exceeded, an unusual situation for any drug, particularly an OTC drug, one placing a large fraction of users close to a toxic dose in the ordinary course of use," the report said

Premranjan Kumar et al

10.3389/fphys.2015.00247 37 GonalvesG

Research Article

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