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This opens the door to complementing existing treatments for alcohol use disorder with a GLP-1 receptor-targeted approach, he adds

Hypoglycemia: low risk alone, but meaningfully elevated when combined with insulin or sulfonylureas

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Impaired Hepatic Function Since impaired hepatic function has been associated with some cases of lactic acidosis, Janumet should generally be avoided in patients with clinical or laboratory evidence of hepatic disease

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