Moreover, gut barrier dysfunction was consistently observed in rodent models following microplastics exposure, marked by reduced expression of tight junction proteinsZO-1, Occludin, Claudin-1, and Claudin-5 (Jiang et al., 2023
5 The eyes are under constant exposure to irradiation and therefore have an extraordinary need for antioxidant protection, with the retinal pigment epithelial being particularly susceptible to oxidative damage
The most actionable approach is tracking the downstream markers that respond to glutathione status: oxidative stress markers, liver enzymes, methylation markers, and inflammation
10.1155/2021/5529913 21 ChangX.ZhangT.WangJ.LiuY.YanP.MengQ.et al (2021b)
As a major intracellular antioxidant, it directly neutralises reactive oxygen species (ROS) and free radicals that accumulate during normal metabolism and are elevated in fatty liver disease
[DOI] [PubMed] [Google Scholar] 104.Howard SC, McCormick J, Pui CH, Buddington RK, Harvey RD