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Toxicant Burden and Sensitivities: By heavily upregulating Phase II liver detoxification enzymes (GSTs) and providing direct heavy metal chelation, NAC helps the body safely process and excrete environmental toxins, potentially reducing systemic chemical sensitivities

Discuss realistic weight loss expectations: ask your doctor what percentage weight loss is achievable given your prednisone dosage and duration

Most importantly, remember that side effects typically improve dramatically after weeks 24

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Given this background, a comprehensive assessment of liver functional reserve, quality-of-life impairment, sleep disturbances, fall risk, and driving habits is essential for both determining treatment initiation and evaluating therapeutic response