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In clinical trials and post-marketing surveillance of patients without these conditions, thyroid cancer has not emerged as an increased risk with long-term semaglutide therapy

Studies suggest that metabolism can decrease by as much as 15% to 25% below the predicted rate, even with the medication actively working fully

Using any substitute compromises your safety and may render the medication unusable

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Another oral, non-peptide GLP-1 RA (lotiglipron) has also been withdrawn from development as in early phase clinical trials resulted in elevated liver enzymes which could indicate liver toxicity [30]

Cutting corners on storage is false economy