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Elossaily would like to thank AlMaarefa University for supporting this research under project number MHIRSP2025-018

Human clinical trials remain limited

Many people think taking too much of a water-soluble vitamin is impossible since, unlike fat-soluble vitamins, water-soluble vitamins are not readily stored in the body, and excess amounts are flushed out of the body in urine

This combination can help boost metabolism, enhance fat breakdown, and promote weight loss

Over time, organisms may exhibit a decline or downregulation of transcription factor cAMP response element-binding protein (CREB) activity in the brain, i.e., cAMP response element binding activity

Feb 28, 2026 A single statistic has been circulating through weight loss forums, Reddit threads, and health news outlets for months now