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Retatrutide monotherapy achieved 24.2% weight reduction in phase 2 trials, while cagrilintide combined with semaglutide (CagriSema) reached 22.7%

Nature 488 (7412), 471475 (2012)

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The statistical differences between the two groups were compared by Students t-test and one-way analysis of variance (ANOVA) for multiple comparisons were used