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This work was supported by the National Institute on Drug Abuse Intramural Research Program (M.F., G.R.M., M.N.N., V.M., O.A.A., M.A.H., and L.L.) and the National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research (M.F., G.R.M., V.M., and L.L.)

Such mild symptoms usually alleviate spontaneously with gradual dose titration and sustained medication for 13 months without permanent drug withdrawal needed

Still, observable findings in study data typically follow a staged timeline: early physiological markers within the first one to two weeks, and measurable body-composition changes generally appearing over a four-to-eight-week research window

Cardiovascular issues : Sinus tachycardia (fast heart rate) has been reported

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SMI, skeletal mass index