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Metabolism of GSH Glutathione, the most plentiful thiol-containing substance of low molecular weight in cells, is a crucial antioxidant and antidote in all mammalian tissues

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A systematic review of 11 studies to date (up to 2023) involving 455 patients with FM and 385 controls has shown consistent gut microbiota dysbiosis, with lower microbial diversity, as measured by lower Shannon indices, along with changes in the gut microbiota composition (31).Reported abnormalities include an altered Bacteroidetes/Firmicutes ratio and aberrant abundance of specific taxa, such as members of the family Lachnospiraceae and the genus Prevotella (32)