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NICE guidance on type 2 diabetes management (NG28) outlines numerous alternative agents, including other GLP-1 receptor agonists, SGLT2 inhibitors, or DPP-4 inhibitors, depending on individual patient factors and treatment goals

Nakagawa, K., Kiko, T., Miyazawa, T., Burdeos, G

Colonic Insl5 and plasma INSL-5 levels are elevated during fasting in calorie-restricted mice and normalize upon refeeding (164)

10.1007/s002130000406 341

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Meanwhile, the phosphorylation level of p38 MAPK was significantly elevated, and its ferroptosis inhibitors, SB202190, reduced ROS production, restored the expression of ferroptosis - related genes, and promoted cell survival by blocking this pathway