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An Nrf2 activator (hydralazine), which reduces ROS production in LECs in mice and humans, provides cytoprotection and delays lens opacification caused by aging and oxidative stress (410)

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Tirzepatide (Mounjaro, Zepbound): A newer medication that targets both GLP-1 and GIP receptors, offering even greater appetite control and blood sugar benefits

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Of these overweight patients, more than 62% were noted to have acanthosis nigricans and it was particularly prominent in the Hispanic and African American children (1)

As a 2021 U.S