Naltrexone/Bupropion ER (Contrave): newly approved treatment option for Chronic Weight Management in obese adults
Abbreviations AASLD: American Association for the Study of Liver Diseases ARR: Absolute risk reduction BMI: Body Mass Index CI: Confidence interval CrI: Credible interval EHR: Electronic Health Record FDA: U.S
Carnitine increases muscular efficiency during high-intensity training, it boosts mental focus and brain function
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The mechanistic basis involves GHK-CuCuSOD1 (cytoplasmic Cu/Zn-SOD) enhanced activity (NBT reduction assay: +31 5%), reducing HO-driven JNK activation via ASK1-Thr845 phosphorylation (ThioredoxinReductase-Trx1 redox buffer maintained)
More new compounds have been added as possible tools for anti-cancer therapies, being characterized by a more selective mechanism and fewer side effects, resulting in better anti-cancer responses and/or fewer side effects
