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This phenomenon is manifested by cellular swelling, plasma membrane rupture, and eventually the disappearance of cellular boundaries

Besides, the transporter is also expressed in other tissues, and independent data (114116) show a less drastic difference between human colonocytes and enterocytes in its expression (Figure 2B), compared to the initial finding of a 10-fold higher expression in the colon relative to other regions of gastrointestinal tract in humans (117)

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Mitochondrial DNA copy numbers in pyramidal neurons are decreased and mitochondrial biogenesis transcriptome signaling is disrupted in Alzheimers disease hippocampi