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In 1951 Conley and Krevans from the Johns Hopkins Hospital challenged the practice, raising the possibility that the neurological manifestations in some new pernicious anemia patients may be linked to previously prescribed high oral doses of folic acid (2028 mg/d) (12)

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Consult a Healthcare Provider: Discontinue the supplement and see your doctor or nutritionist for further advice

B12 (when taken with dexamethasone, an anti-inflammatory steroid medication) has also been shown to increase the activity of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), which promote nerve survival and regeneration

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