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Metabolism 45 (10), 11271137

Mechanistically, delayed gastric emptying is due to cholinergic inhibition of parasympathetic outflow and nitric oxide (NO) release in a cAMP/PKA-dependent manner [37]

Originally developed for type 2 diabetes, Semaglutide GLP-1 has proven highly effective in promoting significant, sustained weight loss by mimicking the hormone GLP-1

However, the latter mechanism is not supported by our experimental findings for two reasons: first, only didepsipeptides and a multiple thereof were found by means of UPLC-TOF MS and not even traces of depsipeptide intermediates showing uneven numbers of monomers were detectable

All other authors of the manuscript do not have a conflict of interest to declare