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In laboratory environments, it is widely used for the preparation, reconstitution, and dilution of lyophilized peptides and other research compounds

This intricate biological process may be explained by the balance between mitochondrial biogenesis and mitophagy under different physiological conditions

However, a comprehensive review published in 2025 emphasized that the majority of this evidence remains preclinical , meaning it was not conducted in large, well-controlled human trials

Iron deposition-induced ferroptosis in alveolar type II cells promotes the development of pulmonary fibrosis

Electrolyte imbalance or kidney strain , particularly if hydration is low or kidney function is already reduced