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After binding of LH-RH, the LH-RH receptor-LH-RH complex is coupled to G 1 protein and activates phosphotyrosine phosphatase, which dephosphorylates receptors for epidermal growth factor (EGF), blocking the signal pathways 3,6

Nordisk Psykiatrisk Tidsskrift, 39(Supplement 11), 4753

L., Chey, W

Specifically, it has been found in "the cerebral cortex, cerebellum, hippocampus, thalamus, striatum, basal forebrain and the brainstem." These brain regions are linked to various cognitive processes from motivation and attention to memory and mood balance

Up to 24.2% body weight reduction after 48 weeks has been observed with higher doses in people with obesity

2018;27(2):450460.e6