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They mimic the GLP-1 hormone released in the gut in response to eating

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Individuals with a history of pulmonary, neurologic, hepatic, rheumatic, hematologic, or renal chronic disease, who were treated with immunosuppressive therapy in the 6 months prior to screening, or who used medication or supplements that may have confounded the study results were also excluded

The mitochondrial membrane potential in isolated mitochondria was assessed in quenching-mode, that is, when the level of Rho123 in the mitochondria is sufficiently high, its emission wavelength shifts towards the red, resulting in a reduction of the fluorescent signal at 527 nm 29

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