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10.1016/j.neuroscience.2011.06.076 53

placebo, ambos en combinacin con insulina, con o sin metformina: En un estudio doble ciego de 52 semanas, se aleatorizaron 731 pacientes con diabetes tipo 2 inadecuadamente controlados con insulina (basal, basal/bolo o premezclada) con o sin metformina para ser tratados con 3 mg de semaglutida, 7 mg de semaglutida, 14 mg de semaglutida o placebo una vez al da

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