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Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears

However, while vitamin B12 appears to be generally safe, more is not necessarily better

Potential heterogeneity was explored with inverse-variance weighted meta-regression analyses and subgroup analysis

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All group means are presented in Table 3

Supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle