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Safety Considerations and Who Should Monitor More Closely Women with polycystic ovary syndrome (PCOS), endometriosis, or dysmenorrhea already experience dysregulated hormonal cycles and heightened GI sensitivity

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Research shows that hormonal changes during the menopause transition can be complex

In particular, lower levels of adiponectin and increased expression of TNF- and its soluble receptor have been recently related to the development of NASH (43)