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This complex process means that conditions affecting the stomach or intestines can significantly impair B12 absorption, including pernicious anaemia, atrophic gastritis, previous gastric surgery, coeliac disease, Crohn's disease, and long-term use of certain medications (such as metformin, proton pump inhibitors, and H2 antagonists)
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The best tablets and capsules use special forms or protective ingredients to get the peptide where it needs to go
Interestingly, metabolite analysis revealed decreased expression of acetyl-CoA, an essential precursor for lipogenesis, and downstream acetyl-CoA metabolites (Fig
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