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Adv Gerontol, 2008

Direct Cost Comparison Monthly Costs: Savings Analysis Compounded vs Brand-Name (No Insurance): Monthly Savings: Low-cost compounded: $720/month savings Mid-range compounded: $620/month savings High-end compounded: $469/month savings Annual Savings: Low-cost compounded: $8,640/year savings Mid-range compounded: $7,440/year savings High-end compounded: $5,628/year savings 18-Month Treatment Savings: Low-cost compounded: $12,960 savings Mid-range compounded: $11,160 savings High-end compounded: $8,442 savings Compounded vs Brand-Name (With Insurance): Compared to Typical Copay ($200/month): Low-cost compounded: $149/month MORE expensive Mid-range compounded: $350/month MORE expensive However: Insurance coverage often denied Prior authorization frequently rejected May lose coverage Deductibles affect cost For insured patients with good coverage, insurance may be cheaperbut coverage is unreliable

Figure 2A ) to screen for compounds with anti-inflammatory activity and novel chemical scaffold

Although the SELECT trial differs from the trials reviewed, most significantly in the recruitment of a population without diabetes (and hence potentially at lower baseline risk), it is encouraging that our calculated NNT 3P-MACE falls within the ranges reported, contributing to the face-validity of our analysis

In people with Type 2 diabetes, tirzepatide 5, 10, and 15 mg were more efficacious in reducing HbA1c compared to semaglutide 0.5, 1.0, and 2.0 mg, respectively, researchers say in a media release