Agha-Mohammadi S, Hurwitz DJ
Activated CB1 receptors block neurotransmitter release by inhibiting voltage-gated Ca 2+ channels, decreasing presynaptic Ca 2+ influx or through the adenylyl cyclase-mediated cAMP/protein kinase A (PKA) pathway [55, 56]
Kaluza J, Larsson SC, Orsini N, Linden A, Wolk A
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Understanding the right dosage and duration guidelines as advised by experts is also crucial
Questions about dose adjustment are appropriate if you have been at the same dose for an extended period without side effects and weight loss has plateaued